Vinorelbine-loaded multifunctional magnetic nanoparticles as anticancer drug delivery systems: synthesis, characterization, and in vitro release study

• Zeynep Özcan and
• Afife Binnaz Hazar Yoruç

Beilstein J. Nanotechnol. 2024, 15, 256–269, doi:10.3762/bjnano.15.24

• , as they increase permeability and retention effect in solid tumors, enabling precise application to the targeted cells. Various structures such as silica-based conjugates, inorganic polymers, ceramic nanomaterials, gold, iron oxide, and noble metal nanoparticles have been utilized [9][10]. Among the

Influence of conductive carbon and MnCo₂O₄ on morphological and electrical properties of hydrogels for electrochemical energy conversion

• Sylwia Pawłowska,
• Karolina Cysewska,
• Yasamin Ziai,
• Jakub Karczewski,
• Piotr Jasiński and
• Sebastian Molin

Beilstein J. Nanotechnol. 2024, 15, 57–70, doi:10.3762/bjnano.15.6

• , drugs, metal nanoparticles, metal oxide nanoparticles, carbon nanotubes, or biomolecules. This is a very important advantage that opens ways of designing composite hydrogels with various properties and applications such as biomedical [8][9][10], biosensors [11][12][13], wearable electronics [14][15][16

Curcumin-loaded nanostructured systems for treatment of leishmaniasis: a review

• Douglas Dourado,
• Thayse Silva Medeiros,
• Éverton do Nascimento Alencar,
• Edijane Matos Sales and
• Fábio Rocha Formiga

Beilstein J. Nanotechnol. 2024, 15, 37–50, doi:10.3762/bjnano.15.4

• in the spleen of mice was around 60% for free-UA and close to 90% for NLC-UA. Confocal microscopy images proved the cell uptake of NLC into macrophages. Metal nanoparticles are also excellent alternatives for carrying antileishmanial drugs [71]. Almayouf et al. produced silver nanoparticles (Ag-NP

Nanotechnological approaches in the treatment of schistosomiasis: an overview

• Lucas Carvalho,
• Michelle Sarcinelli and
• Beatriz Patrício

Beilstein J. Nanotechnol. 2024, 15, 13–25, doi:10.3762/bjnano.15.2

• schistosomiasis due to their characteristics as drug carriers [10], metal nanoparticles usually present intrinsic action even when not loaded with drugs. Works with other parasites suggest that metallic nanoparticles may affect enzyme activity necessary to the physiology and production of the tegument [26

Nanoarchitectonics of photothermal materials to enhance the sensitivity of lateral flow assays

• Elangovan Sarathkumar,
• Rajasekharan S. Anjana and
• Ramapurath S. Jayasree

Beilstein J. Nanotechnol. 2023, 14, 988–1003, doi:10.3762/bjnano.14.82

• material [75]. For example, nanocomposite materials have been developed by combining noble metal nanoparticles (Au–Ag, Au–Pt, and Au–Ag–Pt) or hybrids of noble metals, metals, and/or carbon materials (Au–Fe, Au–carbon, and Au–Fe–carbon). The resultant nanocomposites exhibit properties of all constituents

Ni, Co, Zn, and Cu metal-organic framework-based nanomaterials for electrochemical reduction of CO₂: A review

• Ha Huu Do and
• Hai Bang Truong

Beilstein J. Nanotechnol. 2023, 14, 904–911, doi:10.3762/bjnano.14.74

• within MOFs, thereby enhancing the CO2RR process. Besides, MOFs could be used as ideal precursors for the controlled dispersion of metal nanoparticles within organic frameworks, either through operational conditions or via the pyrolysis technique, thereby promoting efficient CO2 reduction [35][36]. The

Silver-based SERS substrates fabricated using a 3D printed microfluidic device

• Phommachith Sonexai,
• Minh Van Nguyen,
• Bui The Huy and
• Yong-Ill Lee

Beilstein J. Nanotechnol. 2023, 14, 793–803, doi:10.3762/bjnano.14.65

• formation of a charge-transfer complex between chemisorbed species and matrix material, which yields enhancement when the excitation frequency resonates with a charge-transfer transition [7]. Noble metal nanoparticles (NPs) have gained much popularity in various fields, such as analytical chemistry and

Metal-organic framework-based nanomaterials as opto-electrochemical sensors for the detection of antibiotics and hormones: A review

• Akeem Adeyemi Oladipo,
• Saba Derakhshan Oskouei and
• Mustafa Gazi

Beilstein J. Nanotechnol. 2023, 14, 631–673, doi:10.3762/bjnano.14.52

• , which lowers their electrochemical detection performance [64]. Researchers have focused on various research efforts to improve the conductivity and amplify the electrical signals of MOFs by combining them with other highly conductive materials (such as carbon materials, metal nanoparticles, or metal

Plasmonic nanotechnology for photothermal applications – an evaluation

• A. R. Indhu,
• L. Keerthana and
• Gnanaprakash Dharmalingam

Beilstein J. Nanotechnol. 2023, 14, 380–419, doi:10.3762/bjnano.14.33

• materials [7][8], such as Au nanoparticles (AuNPs), in photodynamic therapy [9][10][11]. Metal nanoparticles in general have been extensively explored in PPT applications due to their high free electron density and the possibility of intricate tuning of light absorption [12]. Noble metal nanoparticles with

• the phonon modes leads to an increase in temperature of the metal nanoparticles, and the ultimate conduction of this heat to the surrounding. The exchange time will vary for small nanoparticles due to quantum confinement effects [65] observed when the size of the nanoparticle is comparable to the Bohr

• thermal conductivity and absorption power of the surrounding medium. The temperature increase in the metal nanoparticles (ΔTNP) and thermal capacitance coefficient can be calculated using the following equation [96]: I is the illumination intensity of the laser source, σabs is the absorption cross section

New trends in nanobiotechnology

• Pau-Loke Show,
• Kit Wayne Chew,
• Wee-Jun Ong,
• Sunita Varjani and
• Joon Ching Juan

Beilstein J. Nanotechnol. 2023, 14, 377–379, doi:10.3762/bjnano.14.32

• thematic issue covered topics related to new concepts and ideas pertaining to the design and development of nanobiotechnology. These works include “The role of deep eutectic solvents and carrageenan in synthesizing biocompatible anisotropic metal nanoparticles” [4]. This review sheds light onto significant

• works involving the synthesis of metal nanoparticles using environmentally friendly wet chemical methods in which carrageenan is the main resource. The review summarises the possibility of creating a safe and non-toxic path to the synthesis of nanomaterials while maintaining its properties, such as

• agent for nanomaterials synthesis. The review is concluded providing an outlook of these two components (i.e., deep eutectic solvents and carrageenan) as alternatives for the formation of plasmonic metal nanoparticles. The importance of applying these tools to improve the physicochemical properties and

Quercetin- and caffeic acid-functionalized chitosan-capped colloidal silver nanoparticles: one-pot synthesis, characterization, and anticancer and antibacterial activities

• Akif Hakan Kurt,
• Elif Berna Olutas,
• Fatma Avcioglu,
• Hamza Karakuş,
• Mehmet Ali Sungur,
• Cansu Kara Oztabag and
• Muhammet Yıldırım

Beilstein J. Nanotechnol. 2023, 14, 362–376, doi:10.3762/bjnano.14.31

• range of uses such as antibacterial and antimicrobial agents, healthcare-related products, medical device coatings, anticancer agents, optical sensors, anti-inflammatory agents, biocatalysts, cosmetics, and biosensors [41][42][43][44][45]. The combination of polymer-coated metal nanoparticles

Overview of mechanism and consequences of endothelial leakiness caused by metal and polymeric nanoparticles

• Magdalena Lasak and
• Karol Ciepluch

Beilstein J. Nanotechnol. 2023, 14, 329–338, doi:10.3762/bjnano.14.28

• : endothelial leakiness; metal nanoparticles; NanoEL; nanotoxicity; vascular permeability; Review Introduction The vascular barrier is a highly selective boundary between blood and tissues. Its proper functioning is essential to maintaining homeostasis of the whole organism. Formed from mesodermal endothelial

• whose therapeutic success depends on the effective drug delivery to the target sites through highly selective vascular barriers. A relatively new method that overcomes the endothelial barrier is the use of nanoparticles (NPs), especially different metal nanoparticles, for example, Au or Ti nanoparticles

Combining physical vapor deposition structuration with dealloying for the creation of a highly efficient SERS platform

• Adrien Chauvin,
• Walter Puglisi,
• Damien Thiry,
• Cristina Satriano,
• Rony Snyders and
• Carla Bittencourt

Beilstein J. Nanotechnol. 2023, 14, 83–94, doi:10.3762/bjnano.14.10

• detection properties are mostly observed in noble metal nanoparticles [2][9][10]. Allowed by their localized surface plasmon resonance (LSPR) in the visible region, silver and gold are the most used materials for the preparation of SERS substrates [11][12]. Although Ag has a higher surface plasmon

In search of cytotoxic selectivity on cancer cells with biogenically synthesized Ag/AgCl nanoparticles

• Mitzi J. Ramírez-Hernández,
• Mario Valera-Zaragoza,
• Omar Viñas-Bravo,
• Ariana A. Huerta-Heredia,
• Miguel A. Peña-Rico,
• Erick A. Juarez-Arellano,
• David Paniagua-Vega,
• Eduardo Ramírez-Vargas and
• Saúl Sánchez-Valdes

Beilstein J. Nanotechnol. 2022, 13, 1505–1519, doi:10.3762/bjnano.13.124

• give rise to a collective oscillation known as surface plasmon effect [34]. This effect can be monitored by UV–vis spectroscopy, where metal nanoparticles absorb radiation at different wavelengths depending on their size [36]. The UV–vis absorption spectra of the reactions at different temperatures are

Rapid and sensitive detection of box turtles using an electrochemical DNA biosensor based on a gold/graphene nanocomposite

• Abu Hashem,
• M. A. Motalib Hossain,
• Ab Rahman Marlinda,
• Mohammad Al Mamun,
• Khanom Simarani and
• Mohd Rafie Johan

Beilstein J. Nanotechnol. 2022, 13, 1458–1472, doi:10.3762/bjnano.13.120

• surface-to-volume ratio [37][38][43][44][45][46]. Biomolecules such as DNA may readily modify AuNPs by adding thiol and amine groups via Au–S or Au–N links without losing their activity [38][47]. In electrocatalytic applications, the combination of carbon-based materials with metal nanoparticles has been

Supramolecular assembly of pentamidine and polymeric cyclodextrin bimetallic core–shell nanoarchitectures

• Alexandru-Milentie Hada,
• Nina Burduja,
• Marco Abbate,
• Claudio Stagno,
• Guy Caljon,
• Louis Maes,
• Nicola Micale,
• Massimiliano Cordaro,
• Angela Scala,
• Antonino Mazzaglia and
• Anna Piperno

Beilstein J. Nanotechnol. 2022, 13, 1361–1369, doi:10.3762/bjnano.13.112

• combination of noble metal nanoparticles (NPs) with conventional antimicrobial drugs, are considered the next generation of antimicrobial agents. Therefore, there is an increasing demand for rapid, eco-friendly, and relatively inexpensive synthetic approaches for the preparation of nontoxic metallic

• during the reduction/stabilization of metal NPs was investigated for the first time by NMR spectroscopy. Keywords: antimicrobial agents; bimetallic nanoparticles; gold/silver core–shell; Leishmania; pentamidine; polycyclodextrin; Introduction Noble metal nanoparticles (NPs), in particular those

Detection and imaging of Hg(II) in vivo using glutathione-functionalized gold nanoparticles

• Gufeng Li,
• Shaoqing Li,
• Rui Wang,
• Min Yang,
• Lizhu Zhang,
• Yanli Zhang,
• Wenrong Yang and
• Hongbin Wang

Beilstein J. Nanotechnol. 2022, 13, 549–559, doi:10.3762/bjnano.13.46

• the fluorescent “ON” form. Keywords: cell imaging; fluorescence probes; glutathione; gold nanoparticles; mercury ions; rhodamine 6G derivatives; Introduction Metal nanoparticles have been widely used in the development and construction of sensor systems and drug carriers due to their excellent

Zinc oxide nanostructures for fluorescence and Raman signal enhancement: a review

• Ioana Marica,
• Fran Nekvapil,
• Maria Ștefan,
• Cosmin Farcău and
• Alexandra Falamaș

Beilstein J. Nanotechnol. 2022, 13, 472–490, doi:10.3762/bjnano.13.40

• fluorescence (SEF), these techniques have shown huge potential for applications in biomedicine, biotechnology, and optical sensors. Both methods rely on the high electromagnetic fields created at locations on the surface of plasmonic metal nanoparticles, depending on the geometry of the nanoparticles, their

• as well as on tuning the photoluminescence properties of ZnO nanostructures through combination with metal nanoparticles. This review covers the major recent results of ZnO-based nanostructures used for fluorescence and Raman signal enhancement. The broad range of ZnO and ZnO–metal nanostructures

• noble metal nanoparticles and the molecular fluorescence enhancement in the presence of ZnO alone and in combination with metal nanoparticles are also reviewed. Keywords: fluorescence; surface-enhanced Raman spectroscopy; ZnO–metal nanomaterials; ZnO nanostructures; Introduction Over the last decades

A non-enzymatic electrochemical hydrogen peroxide sensor based on copper oxide nanostructures

• Irena Mihailova,
• Vjaceslavs Gerbreders,
• Marina Krasovska,
• Eriks Sledevskis,
• Valdis Mizers,
• Andrejs Bulanovs and
• Andrejs Ogurcovs

Beilstein J. Nanotechnol. 2022, 13, 424–436, doi:10.3762/bjnano.13.35

• ]. Nanostructured materials are widely used as the working surface of the electrode [47][48][49]. The most common are transition metal nanoparticles [33][37][50][51][52][53][54], carbon nanotubes [8], metal oxides [55][56][57][58][59][60][61][62][63][64], graphene [32][33], and ordered mesoporous carbon [38][65][66

The effect of metal surface nanomorphology on the output performance of a TENG

• Yiru Wang,
• Xin Zhao,
• Yang Liu and
• Wenjun Zhou

Beilstein J. Nanotechnol. 2022, 13, 298–312, doi:10.3762/bjnano.13.25

• concentration, and temperature during the electrodeposition of copper. The samples were characterized using XRD and SEM. The output performance of the TENG is closely related to the size, charge density distribution, and shape of the metal nanoparticles. Keywords: charge density; green energy; metal

• not reduced. Subsequently, the SEM images were analyzed and processed by using the Matlab edge detection algorithm, and the IMOVERLAY script in Matlab File Exchange was used for pixel analysis. Thus, the percentage of the substrate area without metal nanoparticles was calculated by the percentage of

• . There is no potential at this stage, so the transferred charge will accumulate in the gap of metal nanoparticles, and the charge accumulation will have a positive impact on the output performance. However, when the substrate area without nanoparticles is too large, the decrease in the number of metal

Surfactant-free syntheses and pair distribution function analysis of osmium nanoparticles

• Mikkel Juelsholt,
• Jonathan Quinson,
• Emil T. S. Kjær,
• Baiyu Wang,
• Rebecca Pittkowski,
• Susan R. Cooper,
• Tiffany L. Kinnibrugh,
• Søren B. Simonsen,
• Luise Theil Kuhn,
• María Escudero-Escribano and
• Kirsten M. Ø. Jensen

Beilstein J. Nanotechnol. 2022, 13, 230–235, doi:10.3762/bjnano.13.17

• -free synthesis of precious metal nanoparticles (NPs) performed in alkaline low-boiling-point solvents has been recently reported. Monoalcohols are here investigated as solvents and reducing agents to obtain colloidal Os nanoparticles by using low-temperature (<100 °C) surfactant-free syntheses. The

• ] complexes. Keywords: metal nanoparticles; osmium; pair distribution function; surfactant-free synthesis; Findings Precious metals are limited resources, yet fundamental for a range of applications, such as in medicine or catalysis [1][2][3]. There are relatively few reports on osmium (Os) compared to

Sputtering onto liquids: a critical review

• Anastasiya Sergievskaya,
• Adrien Chauvin and
• Stephanos Konstantinidis

Beilstein J. Nanotechnol. 2022, 13, 10–53, doi:10.3762/bjnano.13.2

Self-assembly of amino acids toward functional biomaterials

• Huan Ren,
• Lifang Wu,
• Lina Tan,
• Yanni Bao,
• Yuchen Ma,
• Yong Jin and
• Qianli Zou

Beilstein J. Nanotechnol. 2021, 12, 1140–1150, doi:10.3762/bjnano.12.85

• et al. [62] self-assembled metal nanoparticles with good catalytic activity by coordination of histidine derivatives N-(benzyloxycarbonyl)-ʟ-histidinohydrazide with zinc ions on a minimum design principle. The catalytic performance of p-nitrophenyl acetate hydrolysis to p-nitrophenol was evaluated by

• monitoring the absorbance of p-nitrophenol at 400 nm. The catalytic formation of p-nitrophenol started within the first three minutes and then gradually increased. The catalytic rate constant of metal nanoparticles was higher than that of lipase (6.00 × 10−2 and 6.95 × 10−3 s−1, respectively). In addition

• , the substrate affinity of metal nanoparticles (1.53 mM) is comparable to that of natural lipase (1.27 mM). Metal ions, especially silver ions (Ag+), have been widely studied regarding antibacterial, antifungal, antiviral, anti-inflammatory, anti-angiogenic, and antitumor activities [63][64]. Silver

Assessment of the optical and electrical properties of light-emitting diodes containing carbon-based nanostructures and plasmonic nanoparticles: a review

• Keshav Nagpal,
• Erwan Rauwel,
• Frédérique Ducroquet and
• Protima Rauwel

Beilstein J. Nanotechnol. 2021, 12, 1078–1092, doi:10.3762/bjnano.12.80

• employed in display applications and lighting systems. Further research on LED that incorporates carbon nanostructures and metal nanoparticles exhibiting surface plasmon resonance has demonstrated a significant improvement in device performance. These devices offer lower turn-on voltages, higher external

• as the emissive layer (EML), the hole transport layers (HTL), the electron transport layers (ETL), the cathode, and the anode [17][18][19][20][21]. Enhancement in LED properties via surface plasmon resonance (SPR) of metal nanoparticles (MNP) such as Au and Ag have also been reported [22][23]. This

Progress and innovation of nanostructured sulfur cathodes and metal-free anodes for room-temperature Na–S batteries

• Marina Tabuyo-Martínez,
• Bernd Wicklein and
• Pilar Aranda

Beilstein J. Nanotechnol. 2021, 12, 995–1020, doi:10.3762/bjnano.12.75

• collector. As a result, the sodium polysulfide/MWCNT fabric cathode delivers a discharge capacity of 400 mAh·g−1 after 30 cycles. Transition metal nanoparticles as polysulfide sequestrants and electrocatalysts As discussed above, hollow and porous carbonaceous structures, and in particular nitrogen or

• ]. Therefore, the shuttle effect often cannot be avoided. In order to solve this limitation, transition metal nanoparticles (NPs) or compounds are incorporated in the cathode. The metallic species is bonded to the carbon skeleton creating a dipole, which leads to dipole–dipole interactions with the